North America 25 Sep 2026 · Dr Natalya Mathur
ENCLAI ID ENCLAI-2026-0000440-7 · Cite

16% fewer mpox cases in the US: 95 in the last 30 days

ENCLAI SURVEILLANCE BRIEFING · 25 SEPTEMBER 202616% fewer mpox cases in the US: 95 inthe last 30 daysMpox (monkeypox) · The US · reported cases95reported cases in the 30 days to 25 September▼ 16% fewer than the 30 days before (113)113The 30 daysbefore216Same 30 days, ayear earlier36690 days to 25September1,0402026 so farThree 30-day windows216A year earlier11330 days before95Last 30 daysLargest counts, last 90 daysThe US366The UK166Germany77Australia16Singapore11New Zealand28 countries with a reported count in this windowWhat this briefing shows1Reported cases fell from 113 to 95 between the two latest 30-daywindows, 16% fewer.2The latest count of 95 is below the 216 reported in the same 30days a year earlier.3The US accounts for 51.1% of the mpox cases reported to ENCLAIworldwide in 2026 and ranks 1 of 15 reporting countries.Read with care: reports to official surveillance, not people and not a rate. A change between30-day windows can come from reporting timing as much as from transmission.Source: official surveillance reports compiled by ENCLAI · data as of 2026-09-25 ·enclai.net/newsVerify every figure against the source data before use; ENCLAI does not guarantee accuracy orcompleteness.
  1. Reported cases fell from 113 to 95 between the two latest 30-day windows, 16% fewer.
  2. The latest count of 95 is below the 216 reported in the same 30 days a year earlier.
  3. The US accounts for 51.1% of the mpox cases reported to ENCLAI worldwide in 2026 and ranks 1 of 15 reporting countries.
Customise it in Visual Studio
Largest included reported counts (6 of 8 countries) · 2026-06-27 through 2026-09-25 · source-record dates; coverage varies
United States366
United Kingdom166
Germany77
Australia16
Singapore11
New Zealand2
Mpox (monkeypox) — United States · reported surveillance count · 2026-06-27 through 2026-09-25 · inclusive source-record dates
Mpox (monkeypox) — United States · reported surveillance count · 2026-08-26 through 2026-09-25 · inclusive source-record dates
Mpox (monkeypox) — United States · reported surveillance count · 2026-07-26 through 2026-08-25 · inclusive source-record dates
Mpox (monkeypox) — United States · reported surveillance count · 2025-08-26 through 2025-09-25 · inclusive source-record dates
Mpox (monkeypox) · combined reported surveillance count · 2026-06-27 through 2026-09-25 · inclusive source-record dates
Mpox (monkeypox) · weekly reported-count series · Weeks starting 2026-06-15 through 2026-08-31
Largest included reported counts (6 of 8 countries) · 2026-06-27 through 2026-09-25 · source-record dates; coverage varies

The full briefing

Full 2026 picture: Mpox (monkeypox) in United States — reported cases by year, monthly records and every briefing for this pair.

The US reported 366 mpox cases in the 90 days to 25 September. 95 of them came in the 30 days to 25 September, against 113 in the 30 days before. The same 30 days a year earlier had 216.

Why it matters

The US accounts for 51.1% of the mpox cases reported to ENCLAI worldwide so far in 2026. It ranks 1 of 15 reporting countries.

The numbers

PeriodReported cases
Last 30 days (to 25 September)95
The 30 days before that113
Same 30 days a year earlier216
90 days to 25 September366
2026 so far (ENCLAI export)1,040
The card shows mpox in the US. It compares the last 30 days with the 30 days before, as reported to ENCLAI.
The card shows mpox in the US. It compares the last 30 days with the 30 days before, as reported to ENCLAI.

What the source says

These figures come from official surveillance reports. They count reports, not people. They are not an incidence rate, the rate of new cases in a population. They do not cover the whole population. The reporting periods do not match these dates exactly. Some reports are incomplete or still in progress. Some run past the window. Some reports do not say which date they use: symptom onset, notification, or confirmation.

Caveats

  • A change between two 30-day windows can come from reporting timing as much as from transmission. The source does not say which.

Where to learn more

Mpox (monkeypox) in the US: the 2026 picture · Mpox (monkeypox) worldwide · the US: all diseases · How to read these counts

Retained reporting context

Included reporting countries

Mpox (monkeypox)

641

combined reported surveillance count

2026-06-27 through 2026-09-25 · inclusive source-record dates

For Mpox (monkeypox), the combined reported surveillance count across the 8 countries with positive reported counts in this selection is 641. The selection uses source-record dates 2026-06-27 through 2026-09-25, inclusive. This covers only these reporting countries; source periods and completeness vary.

Exact included country membership
CountryReported countSource-record dates
Australia162026-06-27 through 2026-09-25
Germany772026-06-27 through 2026-09-25
United Kingdom1662026-06-27 through 2026-09-25
Hong Kong12026-06-27 through 2026-09-25
New Zealand22026-06-27 through 2026-09-25
Puerto Rico22026-06-27 through 2026-09-25
Singapore112026-06-27 through 2026-09-25
United States3662026-06-27 through 2026-09-25

Snapshot 2026-09-25

Weekly reporting history

Mpox (monkeypox)

weekly reported-count series

Weeks starting 2026-06-15 through 2026-08-31

A retained retrospective weekly reported-count series across included reporting countries. Country membership and reporting completeness can vary by week. Missing weeks remain gaps. This is a separate report-series measure; it does not establish exact incidence or laboratory confirmation.

Retained weekly report series
WeekReported count
2026-06-15 through 2026-06-2124
2026-06-22 through 2026-06-280
2026-06-29 through 2026-07-0526
2026-07-06 through 2026-07-1220
2026-07-13 through 2026-07-1921
2026-07-20 through 2026-07-2619
2026-07-27 through 2026-08-0273
2026-08-03 through 2026-08-0937
2026-08-10 through 2026-08-1630
2026-08-17 through 2026-08-2337
2026-08-24 through 2026-08-3051
2026-08-31 through 2026-09-0639

Snapshot 2026-09-24

Sources and limitations

  • Window. Each quantity keeps its recorded source-selection dates and coverage notes. Dated batches and weekly or genomic observations retain their separate measures. Publication or capture dates do not establish case onset, equal cohorts or period completeness.
  • Denominator. The retained counts do not establish complete populations, equal reporting cohorts or incidence rates. Source period bounds and definitions can differ.
  • Case definition. Case definitions are set nationally and change over time. Counts for the same disease in different countries may not be counting the same thing.
  • Revisions. Agencies restate figures. Values here are as reported at the time of publication; see the update history below.

ENCLAI counts reflect verified records available from reporting sources for the stated window. They are not estimates of total incidence and should not be interpreted as medical advice. Full methodology: the dataset.

Review and corrections

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