Compiled by the ENCLAI research team following a documented methodology · Editorial oversight: Dr Natalya Mathur, Founder · Data last updated: (UTC)

Mpox (monkeypox) in Mexico: 2026 cases and outbreak reports

Reported mpox (monkeypox) surveillance for Mexico (MEX) — ▲ Rising · 2025 — latest record 2026-10-02

What the 2026 data shows

No mpox (monkeypox) case count has been reported for Mexico so far in 2026. The full year 2025 closed at 789 cases. 2025 closed 263% above the 2023–2024 average, which is why the trend reads “Rising”.

ENCLAI has logged 78 surveillance records for mpox (monkeypox) in Mexico in 2026, with the most detailed reporting in Oct 2026 (78 records). 2 distinct surveillance sources reported this pair in 2026.

Key facts: Mpox (monkeypox)

Transmission
Close contact
Skin-to-skin (including sex), mouth-to-mouth or mouth-to-skin; contaminated linen; mother to child; animal bites or handling.WHO 2024
Incubation
≈ 1 week
Range 1–21 days after exposure.WHO 2024
Vaccine
Yes — high-risk groups
Pre-exposure for health workers, household contacts, people with multiple partners and sex workers; post-exposure within 4 days of contact, up to 14 if symptom-free.WHO 2024

Cited reference facts about the disease, not derived from the surveillance counts on this page. Full set on the Mpox (monkeypox) page.

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Surveillance summary

2026 cases (YTD)
not reported
2025 cases (full year)
789
Baseline avg (3yr)
N/A
Trend (2025)
▲ Rising · 2025
+263% vs 2023–2024 average

Reported cases by year, Mexico

YearReported casesShare of worldwide reports
2023 312 39.8%
2024 123 1.4%
2025 789 18.0%
2026 (year to date) not reported —

Reporting bounds and case definitions vary; historical baselines are a separate comparison measure. Worldwide share compares this country's reported figure with the sum of all countries reporting mpox (monkeypox) to ENCLAI for that year. "Incomplete year" means our sources cover less than ten months of that year, so no full-year figure is shown; "outbreak total to date" is a running total since an outbreak began, not a count for one year.

Surveillance records logged in 2026

MonthRecordsReporting sources
Oct 2026782

A record is one dated surveillance publication or one row of an official table; a month with many records is a month with detailed reporting, not necessarily more cases.

Sub-national reporting, 2026

Areas within Mexico with the most mpox (monkeypox) records this year:

AreaRecords
México2
Mexico City2
Aguascalientes1
Baja California1
Baja California Sur1

Mpox (monkeypox) in other countries, 2026

Country2026 casesTrend
DR Congo 25,392
Uganda 8,498 (outbreak total to date)
Sierra Leone 5,442 (outbreak total to date)
Burundi 4,727
Madagascar 3,534 (outbreak total to date)

Other diseases reported in Mexico, 2026

Disease2026 casesTrend
Measles 13,148
Dengue fever 8,543 ▼ Declining · 2025
Seasonal influenza 7,565 ▼ Declining · 2025
COVID-19 3,057 ▼ Declining · 2025

Questions about this page

How many mpox (monkeypox) cases has Mexico reported in 2026?
No mpox (monkeypox) case count has been reported for Mexico so far in 2026. The full year 2025 closed at 789 cases. 2025 closed 263% above the 2023–2024 average, which is why the trend reads “Rising”.
Is mpox (monkeypox) rising or falling in Mexico?
ENCLAI's trend reading for mpox (monkeypox) in Mexico is “Rising · 2025”: the latest complete year is compared with the earlier baseline from the reported counts; the current year is not judged until it closes.

About this data

Figures are reported case counts as published by the originating health authorities, compiled by ENCLAI from 444 verified surveillance sources. Mexico figures reflect the reporting available to ENCLAI; reporting periods and case definitions differ between sources, and a missing report does not establish zero cases. ENCLAI holds mpox (monkeypox) records for Mexico dated from 2022. How we verify and update data: methodology & Trust Center · understanding case counts.

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The daily disease brief

One email a day: what changed in official disease reporting worldwide, with the source named for every number. Reported facts only — no forecasts and no interpretation.

Double opt-in — we send a confirmation link and nothing else until you click it. One-click unsubscribe on every email. See our privacy notice.