Compiled by the ENCLAI research team following a documented methodology · Editorial oversight: Dr Natalya Mathur, Founder · Data last updated: (UTC)

Cholera in United States: 2026 cases and outbreak reports

Reported cholera surveillance for United States (USA) — ▼ Declining · 2025 — latest record 2026-10-25

What the 2026 data shows

As of 25 October 2026, the United States has reported 4 cholera cases in 2026, as published by CDC NNDSS Weekly Notifiable Diseases (State-Level). The full year 2025 closed at 5 cases. The three-year baseline for United States is 942 cases a year. 2025 closed 100% below 3yr avg (WHO historical series), which is why the trend reads “Declining”.

Of the 33 countries reporting cholera to ENCLAI in 2026, United States accounts for 0.0% of reported cases and ranks 28 by case count.

ENCLAI has logged 185 surveillance records for cholera in United States in 2026, with the most detailed reporting in Oct 2026 (59 records). 28 of those arrived in the last 30 days; the case counts run to 2026-10-25. 2 distinct surveillance sources reported this pair in 2026.

Reporting authorities for these counts: CDC NNDSS Weekly Notifiable Diseases (State-Level)

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Surveillance summary

2026 cases (YTD)
4
2025 cases (full year)
5
Baseline avg (3yr)
942
Trend (2025)
▼ Declining · 2025
-99% vs 3yr avg

Reported cases by year, United States

YearReported casesShare of worldwide reports
2023 not reported —
2024 not reported —
2025 5 0.0%
2026 (year to date) 4 0.0%

Reporting bounds and case definitions vary; historical baselines are a separate comparison measure. Worldwide share compares this country's reported figure with the sum of all countries reporting cholera to ENCLAI for that year. "Incomplete year" means our sources cover less than ten months of that year, so no full-year figure is shown; "outbreak total to date" is a running total since an outbreak began, not a count for one year.

Surveillance records logged in 2026

MonthRecordsReporting sources
Jan 202641
Mar 202661
Apr 202681
May 2026101
Jun 202681
Jul 2026262
Aug 2026342
Sep 2026302
Oct 2026592

A record is one dated surveillance publication or one row of an official table; a month with many records is a month with detailed reporting, not necessarily more cases. 28 records were logged in the last 30 days.

Sub-national reporting, 2026

Areas within United States with the most cholera records this year:

AreaRecords
New Jersey33
Louisiana13
Virginia7
Florida1
Illinois1

Cholera in other countries, 2026

Country2026 casesTrend
Nigeria 70,323 ▲ Rising · 2025
DR Congo 47,165 ▲ Rising · 2025
South Sudan 14,369 ▲ Rising · 2025
Mozambique 8,060 ▼ Declining · 2025
Yemen 7,081 ▼ Declining · 2025

Other diseases reported in United States, 2026

Disease2026 casesTrend
Chlamydia infection 620,278
Gonococcal infection 202,064
Hepatitis C 62,543 ▲ Rising · 2025
Campylobacteriosis 38,167 ▲ Rising · 2025
Non-typhoidal salmonellosis 26,618

Questions about this page

How many cholera cases has United States reported in 2026?
As of 25 October 2026, the United States has reported 4 cholera cases in 2026, as published by CDC NNDSS Weekly Notifiable Diseases (State-Level). The full year 2025 closed at 5 cases. The three-year baseline for United States is 942 cases a year. 2025 closed 100% below 3yr avg (WHO historical series), which is why the trend reads “Declining”.
Is cholera rising or falling in United States?
ENCLAI's trend reading for cholera in United States is “Declining · 2025”: the latest complete year is compared with the earlier baseline from the reported counts; the current year is not judged until it closes.
Where does United States publish cholera surveillance data?
The counts on this page were published by CDC NNDSS Weekly Notifiable Diseases (State-Level). ENCLAI compiles and normalises them and is not affiliated with these authorities.

About this data

Figures are reported case counts as published by the originating health authorities, compiled by ENCLAI from 444 verified surveillance sources. United States figures reflect the reporting available to ENCLAI; reporting periods and case definitions differ between sources, and a missing report does not establish zero cases. ENCLAI holds cholera records for United States dated from 2025. How we verify and update data: methodology & Trust Center · understanding case counts.

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One email a day: what changed in official disease reporting worldwide, with the source named for every number. Reported facts only — no forecasts and no interpretation.

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